In the health delivery system, the laboratory provides diagnostics and plays an important role in disease control, patient care, and disease surveillance. However, laboratory services are often neglected in health delivery systems in poor and developing countries. Laboratories often have shortages of skilled staff, are poorly funded, often fail to meet safety standards and thus fail accreditation, and experience weak supply chain management systems. Many developing countries also do not have a national policy on laboratory services which further compromises the quality of laboratory services. In this virtual expert panel, members and experts in 37 countries exchange experience and offer input on various challenges.