Here is an article by Alebie, et al. (2017) summarizing antimalaria herbal plants found in Ethiopia. We have a plethora of them, in which we can find alternatives to ACTS when time comes.
Background: Ethiopia is endowed with abundant medicinal plant resources and traditional medicinal practices.
However, available research evidence on indigenous anti-malarial plants is highly fragmented in the country. The
present systematic review attempted to explore, synthesize and compile ethno-medicinal research evidence on antimalarial
medicinal plants in Ethiopia.
Methods: A systematic web search analysis and review was conducted on research literature pertaining to medicinal
plants used for traditional malaria treatment in Ethiopia. Data were collected from a total of 82 Ethiopian studies
meeting specifc inclusion criteria including published research articles and unpublished thesis reports. SPSS Version
16 was used to summarize relevant ethno-botanical/medicinal information using descriptive statistics, frequency,
percentage, tables, and bar graphs.
Results: A total of 200 diferent plant species (from 71 families) used for traditional malaria treatment were identifed
in diferent parts of Ethiopia. Distribution and usage pattern of anti-malarial plants showed substantial variability
across diferent geographic settings. A higher diversity of anti-malarial plants was reported from western and southwestern
parts of the country. Analysis of ethno-medicinal recipes indicated that mainly fresh leaves were used for
preparation of remedies. Decoction, concoction and eating/chewing were found to be the most frequently employed
herbal remedy preparation methods. Notably, anti-malarial herbal remedies were administered by oral route. Information
on potential side efects of anti-malarial herbal preparations was patchy. However, some anti-malarial plants were
reported to have potentially serious side efects using diferent local antidotes and some specifc contra-indications.
Conclusion: The study highlighted a rich diversity of indigenous anti-malarial medicinal plants with equally divergent
herbal remedy preparation and use pattern in Ethiopia. Baseline information gaps were observed in key geographic
settings. Likewise, herbal remedy toxicity risks and countermeasures generally entailed more exhaustive
investigation. Experimental research and advanced chemical analysis are also required to validate the therapeutic
potential of anti-malarial compounds from promising plant species.
Link leads to: https://malariajournal.biomedcentral.com/track/pdf/10.1186/s12936-017-1953-2?site=malariajournal.biomedcentral.com