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Traditional anti-malarial plants in Ethiopia

By Pierre Bush, PhD Moderator | 05 Aug, 2017

Dear Colleagues,
Here is an article by Alebie, et al. (2017) summarizing antimalaria herbal plants found in Ethiopia. We have a plethora of them, in which we can find alternatives to ACTS when time comes.
Highest Regards,

Abstract
Background: Ethiopia is endowed with abundant medicinal plant resources and traditional medicinal practices.
However, available research evidence on indigenous anti-malarial plants is highly fragmented in the country. The
present systematic review attempted to explore, synthesize and compile ethno-medicinal research evidence on antimalarial
medicinal plants in Ethiopia.
Methods: A systematic web search analysis and review was conducted on research literature pertaining to medicinal
plants used for traditional malaria treatment in Ethiopia. Data were collected from a total of 82 Ethiopian studies
meeting specifc inclusion criteria including published research articles and unpublished thesis reports. SPSS Version
16 was used to summarize relevant ethno-botanical/medicinal information using descriptive statistics, frequency,
percentage, tables, and bar graphs.
Results: A total of 200 diferent plant species (from 71 families) used for traditional malaria treatment were identifed
in diferent parts of Ethiopia. Distribution and usage pattern of anti-malarial plants showed substantial variability
across diferent geographic settings. A higher diversity of anti-malarial plants was reported from western and southwestern
parts of the country. Analysis of ethno-medicinal recipes indicated that mainly fresh leaves were used for
preparation of remedies. Decoction, concoction and eating/chewing were found to be the most frequently employed
herbal remedy preparation methods. Notably, anti-malarial herbal remedies were administered by oral route. Information
on potential side efects of anti-malarial herbal preparations was patchy. However, some anti-malarial plants were
reported to have potentially serious side efects using diferent local antidotes and some specifc contra-indications.
Conclusion: The study highlighted a rich diversity of indigenous anti-malarial medicinal plants with equally divergent
herbal remedy preparation and use pattern in Ethiopia. Baseline information gaps were observed in key geographic
settings. Likewise, herbal remedy toxicity risks and countermeasures generally entailed more exhaustive
investigation. Experimental research and advanced chemical analysis are also required to validate the therapeutic
potential of anti-malarial compounds from promising plant species.

Attached resource:

Replies

 

NIRMAL GHIMIRE Replied at 7:42 AM, 6 Aug 2017

how we interrupt malaria life cycle in mosquitoes? except insecticides
. any drugs may be of benefit

Garikai Malunga Replied at 1:04 PM, 6 Aug 2017

Thank you so much Dr Pierre Bush for sharing with us this marvelous article on anti-malaria herbs in Ethiopia. I think that we need to focus on herbal medicine since synthetic drugs are having problems of resistance. Lots of researches have been done on anti-malaria herbs but why are they not available on the commercial market?.

Maimunat Alex-Adeomi Moderator Replied at 4:18 PM, 7 Aug 2017

Thank you Pierre for this very interesting article.

While not a hot topic in malaria control and elimination, the conversation has definitely been around for a while. See attached with a similar systematic review done by Adebayo et al in 2011 in Nigeria and published in the Journal of Ethnopharmacology on plants with antimalarial properties in the country.

Regards,
Maimunat

Attached resource:

Pierre Bush, PhD Moderator Replied at 8:00 PM, 7 Aug 2017

Thank you Maimunat. In fact the whole World is full of Antimarial plants! Wilcox and Bodeker (2009) showed that the plant Vernonia amygdalina can treat uncomplicated malaria in Uganda. The literature review on traditional herbal medicines conducted by this writer has demonstrated that many plants can be used to treat malaria! Etnobiologists/pharmologists have a wide array of plants to look into. The detailed literature review mentioned above can be found in my dissertation in PROQUEST:
https://search.proquest.com/docview/1552714403. To view the chapter, one has to order a copy.
Highest Regards.

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