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MDR-TB Treatment & Prevention

Infection control trends July 2019 edition is dedicated to Tuberculosis

Dr Dhruv Mamtora - June 10, 2019
dear all, I am happy to inform that Infection control trends July 2019 edition is dedicated to Tuberculosis. since India is strongly committed to eliminate tuberculosis and WHO theme is on end TB s...
Keywords:
Advocacy & Education Clinical Assistance Laboratory Program Management Publications & Research technical assistance Training
MDR-TB Treatment & Prevention

WHO recommendation of injectable-free regimens for the treatment of RR/MDR-TB*

Prince James - Aug. 19, 2018
- Can we justify avoiding a Bactericidal drug like Amikacin for MDR TB cases in areas where Bedaquiline is not freely available to every patient of RR / MDR TB like in India? Injectible free regi...
Keywords:
Clinical Assistance Guidelines
MDR-TB Treatment & Prevention

WHO new grouping of drugs for MDR / RR TB

Prince James - Aug. 19, 2018
Administering multiple doses of Imipenem / Meropenem and their huge cost makes their application more difficult than Amikacin - which is placed lower than Imipenem in the new grouping of drugs. Shou...
Keywords:
Advocacy & Education Clinical Assistance Guidelines
MDR-TB Treatment & Prevention

Simultaneous TB/HCV treatment

Svetlana Degtyareva - June 6, 2018
Dear colleagues! Does anyone of you have an experience of simultaneous treatment of a patient with anti-tuberculous and direct acting antiviral drugs for HCV-infection? What are the official approac...
Keywords:
Clinical Assistance Guidelines Publications & Research
MDR-TB Treatment & Prevention

Discordant results of GenXPert

Beatriz Alonso - April 28, 2018
South Sudan. Patient of 38 years old. HIV + on second line and defaulter during 3 months. No previous history of TB. She came back into care with loss of weight, Kaposi sarcoma on mouth , anemia and c...
Keywords:
Clinical Assistance
MDR-TB Treatment & Prevention

Newborns of MDR patient

Betsy dinawanao - Feb. 24, 2018
can I ask a basic question.. can I add a question... can a newborn of an MDR patient be a candidate for BCG vaccine...? thanks and; if a child of an MDR patient shows signs and symptoms suggesti...
Keywords:
Advocacy & Education Clinical Assistance Guidelines Laboratory
MDR-TB Treatment & Prevention

Culture negative TB treatment regimens in those with adverse drug reactions

andrew rosser - Feb. 22, 2018
Dear All, I was after some advice about the treatment of culture negative TB in those patients who have had an adverse drug reaction. I saw an HIV patient who has pulmonary and abdominal radiologic...
Keywords:
Clinical Assistance Guidelines
MDR-TB Treatment & Prevention

PZA resistance in M.fortuitum

Ranjan Perera - Feb. 14, 2018
Is M.fortuitum naturally pyrazinamide resistant all the time? PZA resistance in M.fortuitum Ranjan Perera
Keywords:
Clinical Assistance Guidelines Laboratory Publications & Research technical assistance
MDR-TB Treatment & Prevention

program officer

Mesfin Bekele - Jan. 31, 2018
Focus area of TB/HIV,DR-TB and TBIC and TB/DM program officer Mesfin Bekele Eleanor Bergren
Keywords:
Clinical Assistance Conferences Guidelines Program Management Training
MDR-TB Treatment & Prevention

Bedaquiline and Delamanid beyond 6 months

Ignacio Monedero - Oct. 23, 2017
Dear all I am Ignacio Monedero from the Union. After the recent TB conference in Guadalajara I heard about different experiences of countries and physicians using Bdq and Del for longer than 6 month...
Keywords:
Clinical Assistance Conferences
MDR-TB Treatment & Prevention

2 important publications on newer TB drugs

Erica Lessem - Sept. 7, 2017
Dear all, Please see below two important recent publications on the use of bedaquiline and delamanid (full disclosure-- I am co-author on first piece) The first describes how to choose between b...
Keywords:
Adolescents and Young Adults Advocacy & Education Bedaquiline children Clinical Assistance delamanid Publications & Research technical assistance Training
MDR-TB Treatment & Prevention

role of ESR or CRP to exclude TB and role of complete blood picture in diagnosis of TB

Thant Aung - Aug. 29, 2017
Dear all, I am a medical officer working in Myanmar. I wonder the role of ESR and CRP in diagnosis of TB and if these tests are normal, can we exclude TB? In sputum smear negative presumptive TB pati...
Keywords:
Clinical Assistance Laboratory
MDR-TB Treatment & Prevention

Improving political commitment towards laboratory strengthening

Ranjan Perera - July 15, 2017
This question is for those who have experience in working in Low and Middle income countries supporting laboratory systems. As NGO or private sector partners what are the best ways to improve gover...
Keywords:
Advocacy & Education Clinical Assistance Conferences Guidelines Laboratory Program Management Publications & Research technical assistance Training
MDR-TB Treatment & Prevention

Can we do Clinical trial for new MDR-TB in Africa? What are ways to step forward.

Akshaya Bhagavathula - July 11, 2017
Dear GHD members, Greetings, I am Dr. Akshaya Srikanth Bhagavathula, working as Asst.prof of clinical pharmacy at University of Gondar, Ethiopia from past 5 years. Being health professional, my...
Keywords:
africa african health ministers Clinical Assistance Clinical Trial drug efficacy Ethiopia Guidelines MDRTB TB MDR drug efficacy
MDR-TB Treatment & Prevention

WHI recomendations for SL-LPA

Ranjan Perera - July 10, 2017
What is the latest WHO recomendations for SL-LPA? Is there a seperate recommendation for SL-LPA version 2? WHI recomendations for SL-LPA Ranjan Perera Mohammed suaudi Hassen
Keywords:
Advocacy & Education Clinical Assistance Conferences Guidelines Laboratory Program Management Publications & Research technical assistance Training
MDR-TB Treatment & Prevention

Call for Proposals: Better, shorter treatment for multidrug-resistant TB

Masoud Dara, MD - May 22, 2017
Dear colleagues, UNITAID has launched a call for proposals for better and shorter treatment for MDR-TB https://www.unitaid.eu/call-proposals-better-shorter-treatment-multidrug-resistant-tb-mdr-tb...
Keywords:
Clinical Assistance Publications & Research technical assistance
MDR-TB Treatment & Prevention

sensitivity of GeneXpert with urine samples

Pratibha Narang - April 26, 2017
We have now sufficient reports on sensitivity and specificity of GeneXpert TB/RIF on extrapulmonary tuberculosis but most of the findings are pertaining to CSF, lymph nodes ,tissues, pleural or perito...
Keywords:
Clinical Assistance Laboratory
MDR-TB Treatment & Prevention

Gene Xpert Positive after Anti TB treatment completed

Ram Datt BHATT - April 24, 2017
Any study on; how long after the anti TB treated patient remain the gene Xpert positive due to dead bacilli and its remaining DNA fragment in expectorated sputum? Gene Xpert Positive after Anti TB tre...
Keywords:
Clinical Assistance Guidelines Laboratory Publications & Research technical assistance
MDR-TB Treatment & Prevention

Are there vaccine on research for MDR-TB and XDR-TB.

saurav hamal - April 10, 2017
BCG came a long way from 1921 to 2017, protecting thousands of people from TB, and we now stand in the midst of MDR and XDR TB, do BCG confer protection against them as well, are there some trials goi...
Keywords:
Advocacy & Education Clinical Assistance Guidelines Laboratory Publications & Research technical assistance
MDR-TB Treatment & Prevention

MDR prevention.

saurav hamal - April 4, 2017
We commonly see drug induced liver injury following Start of ATT, now once it develops we hold the drugs and wait to improve the liver function and then again restart the drug. Do this approach contr...
Keywords:
Clinical Assistance Guidelines