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Malaria Treatment & Prevention

World Malaria Report 2018

Pierre Bush, PhD - Nov. 23, 2018
Dear Colleagues, Please find attached the World Malaria Report 2018. The striking point in it is that the progress to eliminate malaria has stalled. The 10 most malaria burdened countries saw an incr...
Keywords:
Diagnostics & Treatment funding policy prevention Vector Control
Malaria Treatment & Prevention

Strategy to improve malaria surveillance system preventing transfusion-transmitted malaria in blood banks using molecular diagnostic

Pierre Bush, PhD - Oct. 3, 2018
Dear Colleagues, Surveillance is an important component of the elements required in the implementation of the strategies for the control, and the elimination of malaria. One way malaria parasites are...
Keywords:
Diagnostics & Treatment policy prevention
Malaria Treatment & Prevention

How do do they get parenteral antimalaria drugs? Private sector drug shops frequently dispense parenteral anti-malarials in a rural region of Western Uganda

Pierre Bush, PhD - Aug. 27, 2018
Dear Colleagues, Would you like to discuss this issue? How do unregulated drug shops get parenteral anti-malaria drugs?It appears that in western Uganda, people who are feeling ill and suspect that t...
Keywords:
Diagnostics & Treatment
Malaria Treatment & Prevention

Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL):

Pierre Bush, PhD - May 25, 2018
Dear Colleagues, High dose Ivermectin combined with dihydroartemisinin-piperaquine reduced the mosquitoe survival in a randomized, double blind placebo controlled trial in Kenya. See Smit et al....
Keywords:
Diagnostics & Treatment prevention Vector Control
Malaria Treatment & Prevention

Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis

Pierre Bush, PhD - May 4, 2018
Dear Colleagues, Plasmodium falciparum is notorious for developing resistance to a number of drugs. It would be a breakthrough if we could be able to uncover all the genes that are responsible for t...
Keywords:
Diagnostics & Treatment prevention Vector Control
Malaria Treatment & Prevention

Simultaneous detection of Plasmodium vivax dhfr, dhps, mdr1 and crt-o resistance-associated mutations in the Colombian Amazonian region

Pierre Bush, PhD - March 30, 2018
Dear Colleagues, Here is an interesting article on Plasmodium vivax genetic mutation, that could help us understand the pattern of resistance to drugs developed by this plasmodium species in some are...
Keywords:
Diagnostics & Treatment prevention Vector Control
Malaria Treatment & Prevention

Get a 360 view of infectious disease diagnostics this Summer in Montreal!

Dear colleagues, The McGill Summer Institute in Infectious Diseases and Global Health will be holding the fourth edition of its Global Health Diagnostics course. As you know, diagnosis is a critica...
Keywords:
Conferences & Events Diagnostics & Treatment education and training global health training prevention
Malaria Treatment & Prevention

Sudden spleen rupture in a Plasmodium vivax-infected patient undergoing malaria treatment

Pierre Bush, PhD - Feb. 14, 2018
Dear Colleagues, Here is an interesting case (written by Elizalde-Torrent et al., 2018) of a sudden spleen rupture due Plasmodium vivax. How many of you have seen cases like this one and what is you...
Keywords:
Diagnostics & Treatment prevention
Malaria Treatment & Prevention

Methylene blue induced morphological deformations in Plasmodium falciparum gametocytes: implications for transmission-blocking

Pierre Bush, PhD - Jan. 9, 2018
Dear Colleagues, As we pursue the fight against the malaria scourge, all innovations are encouraged. Transmission blocking drugs are not that many. Primaquine is a good one for this purpose, but it h...
Keywords:
Diagnostics & Treatment prevention Vector Control
Malaria Treatment & Prevention

Imported malaria in Des Moines, IS

Pierre Bush, PhD - Oct. 28, 2017
Dear Colleagues, A month and half ago I was examining a hematology slide on cellavision when I saw these Plasmosdia falciparum gametocytes. The patient had traveled to Sudan a month before! We saved ...
Keywords:
Diagnostics & Treatment
Malaria Treatment & Prevention

Placental malaria.

Pierre Bush, PhD - Sept. 17, 2017
Dear Colleagues, Placental malaria is a serious condition (see Omer et al., 2017). How can its detection be enhanced? Abstract Background Malaria infection during pregnancy can result in place...
Keywords:
Diagnostics & Treatment prevention
Malaria Treatment & Prevention

Cryptic Plasmodium ovale concurrent with mixed Plasmodium falciparum and Plasmodium malariae infection in two children from Central African Republic

Pierre Bush, PhD - Aug. 18, 2017
Dear Colleagues, Here is a case that most of us would struggle to diagnose properly in the absence of molecular testing help. Highest regards. Abstract Background Since several malaria parasite...
Keywords:
Diagnostics & Treatment prevention
Malaria Treatment & Prevention

Penicillin prophylaxis for patients with hyper-reactive malarial splenomegaly

Rebecca Cook - Aug. 15, 2017
Dear all, We are starting to enroll patients with hyper-reactive malarial splenomegaly (also known as tropical splenomegaly) in our NCD clinic in Liberia. The evidence is fairly clear in terms of t...
Keywords:
Diagnostics & Treatment
Malaria Treatment & Prevention

Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays

Pierre Bush, PhD - Aug. 6, 2017
Dear Colleagues, Here is the news in malaria methodologies Abstract: Background Mosquito-feeding assays are important tools to guide the development and support the evaluation of transmission-bloc...
Keywords:
Diagnostics & Treatment prevention Vector Control
Malaria Treatment & Prevention

Traditional anti-malarial plants in Ethiopia

Pierre Bush, PhD - Aug. 5, 2017
Dear Colleagues, Here is an article by Alebie, et al. (2017) summarizing antimalaria herbal plants found in Ethiopia. We have a plethora of them, in which we can find alternatives to ACTS when time c...
Keywords:
Diagnostics & Treatment policy prevention
Malaria Treatment & Prevention

In the news: Gambia Poised to Become 4th Country to Eliminate Malaria

Pierre Bush, PhD - July 16, 2017
Dear Colleagues, Many malaria endemic countries have received aid from the USA and other donors in the fight against malaria. One country: the Gambia has used the aid very wisely. They are on the pat...
Keywords:
Diagnostics & Treatment funding prevention Vector Control
Malaria Treatment & Prevention

Paperfuge for malaria diagnosis

Sungano Mharakurwa - June 29, 2017
Hi, I thought to share the attached article, where Bhamla et al demonstrate use of the simplest, cheapest (paper-based) centrifuge in malaria diagnosis and several other applications. Paperfuge for m...
Keywords:
Diagnostics & Treatment
Malaria Treatment & Prevention

Malaria elimination: the factors that hinders the progress to quick elimination; a meta analysis.

Pierre Bush, PhD - June 24, 2017
Dear Colleagues, I have a project and I am inviting those who are willing to collaborate to come forward. Most of it involves literature review. You may post the pertinent material under this discuss...
Keywords:
Diagnostics & Treatment prevention
Malaria Treatment & Prevention

Decision-Making (DM) Tools for Malaria Control and Elimination

Vilas Mandlekar - June 5, 2017
Malaria is on the decline in many Malaria endemic countries over the past 10 years. In this context, one of the important determinants for successful administration of a malaria control and eliminatio...
Keywords:
Conferences & Events Diagnostics & Treatment Operations & Logistics policy prevention Vector Control
Malaria Treatment & Prevention

The impact of changing climate conditions on Malaria transmission

Pierre Bush, PhD - June 4, 2017
Dear Colleagues, As several malaria endemic countries aim at eliminating the disease in the next decade, some of them are using all the tools necessary to achieve the goal. Swaziland is experimenting...
Keywords:
Diagnostics & Treatment prevention Vector Control