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MDR-TB Treatment & Prevention

Cochrane review on Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance

Madhukar Pai - Aug. 28, 2018
Please see this new Cochrane systematic review on Xpert for EPTB: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012768.pub2/abstract PDF attached. Cochrane review on Xpert® MTB/RIF...
Keywords:
extrapulmonary TB GeneXpert MTB/RIF
Global Health Diagnostics

Cochrane review on Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance

Madhukar Pai - Aug. 27, 2018
Please see this new Cochrane systematic review on Xpert for EPTB: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012768.pub2/abstract PDF attached. Cochrane review on Xpert® MTB/RIF...
Keywords:
extrapulmonary TB GeneXpert MTB/RIF systematic review
Global Health Diagnostics

Market penetration of Xpert MTB/RIF in high tuberculosis burden countries: A trend analysis

Madhukar Pai - July 26, 2018
Please see this new paper: https://gatesopenresearch.org/articles/2-35/v1 Best Madhu Market penetration of Xpert MTB/RIF in high tuberculosis burden countries: A trend analysis Madhukar Pai
Keywords:
GeneXpert MTB/RIF market trends tuberculosis
MDR-TB Treatment & Prevention

Market penetration of Xpert MTB/RIF in high tuberculosis burden countries: A trend analysis

Madhukar Pai - July 26, 2018
Please see this new paper: https://gatesopenresearch.org/articles/2-35/v1 Best Madhu Market penetration of Xpert MTB/RIF in high tuberculosis burden countries: A trend analysis Madhukar Pai A...
Keywords:
GeneXpert MTB/RIF market trends
Global Health Diagnostics

New TB tools need to be affordable in the private sector: The case study of Xpert MTB/RIF

Madhukar Pai - May 7, 2018
Please see this new paper, which includes updated data on what patients pay for Xpert MTB/RIF testing in the private health sector in highly privatized health markets. It is an update of a previous st...
Keywords:
access to diagnostics GeneXpert MTB/RIF pricing private sector health tuberculosis
Global Health Diagnostics

“Before Xpert I only had my expertise”: A qualitative study on the utilization and effects of Xpert technology among pediatricians in 4 Indian cities

Marlon L. Bayot - May 2, 2018
Sharing with you this interesting study which may reflect the same scenarios regarding the use of Xpert in your country or locality. URL: http://journals.plos.org/plosone/article?id=10.1371/journal...
Keywords:
diagnosis Essential diagnostics list GeneXpert MTB/RIF Pediatric
Global Health Diagnostics

GeneXpert Omni - Hype or Hope? Concerns from the global diagnositc community

Kathleen England - Jan. 29, 2018
In 2015, Cepheid presented their prototype point-of-care device, GeneXpert Omni, a single-module battery powered platform expected to extend testing below district-level in remote settings. Since intr...
Keywords:
diagnosis GeneXpert MTB/RIF HIV early infant diagnosis HIV viral load testing tuberculosis
MDR-TB Treatment & Prevention

GeneXpert Omni - Hype or Hope? Concerns from the global diagnostic community

Kathleen England - Jan. 29, 2018
In 2015, Cepheid presented their prototype point-of-care device, GeneXpert Omni, a single-module battery powered platform expected to extend testing below district-level in remote settings. Since intr...
Keywords:
GeneXpert MTB/RIF POC tests Rapid diagnosis of TB and Rif resistance Remote Settings
Global Health Diagnostics

Challenges in implementing GeneXpert

Ranjan Perera - Sept. 5, 2017
What are the main challenges encountered during GeneXpert implementation in developing countries? Challenges in implementing GeneXpert Ranjan Perera Sunday Chinenye Kathleen England Alaine Umubyeyi Ny...
Keywords:
drug resistant tuberculosis GeneXpert MTB/RIF laboratory service
MDR-TB Treatment & Prevention

The Childhood TB learning portal

Elham Elhshik - June 16, 2017
I just finished the two courses in "the Childhood TB learning portal" produced by The International Union Against Tuberculosis and Lung Disease (The Union). These courses were very helpful for me t...
Keywords:
children genexpert GeneXpert MTB/RIF MDR-TB Pediatric MDR-TB
Global Health Diagnostics

GeneXpert "dust deterioration"

Team! I'm acquiring a GeneXpert MTB/RIF machine for research activities in rural Africa. I expect a fairly small volume of specimens and according to my calculations I might be short with a 2-modu...
Keywords:
GeneXpert MTB/RIF
Global Health Diagnostics

How do we tackle the problem of under-utilization of good diagnostic technologies?

Madhukar Pai - Feb. 11, 2017
Please see this new, large 18 country analysis of Xpert implementation. The authors report that a majority of the sites had access to Xpert, but only 4% of TB/HIV co-infected patients in this cohort w...
Keywords:
access to diagnostics GeneXpert MTB/RIF tuberculosis
MDR-TB Treatment & Prevention

NAAT sensitivity for intrinsic drug resistance

Ranjan Perera - Aug. 6, 2016
If I am correct, NAAT mainly targets only on the potential genetic mutations that can occur in the TB genome. But apart from the mutations, cell wall efflux mechanisms that naturally occur in the baci...
Keywords:
Advocacy & Education Clinical Assistance Clinical Diagnostics Conferences Genetics GeneXpert MTB/RIF Guidelines Laboratory Publications & Research technical assistance Training
MDR-TB Treatment & Prevention

Genexpert Rif R, LPA and DST Rif S

Ranjan Perera - Aug. 4, 2016
Dear experts We have a patient with Genexpert Rif R, HAIN Rif S, INH R and MGIT DST Rif S and INH S. We did a GeneXpert for DST growth control and the result showed Rif R. Repeated HAIN resul...
Keywords:
Clinical Assistance GeneXpert MTB/RIF Laboratory line probe assay Program Management Publications & Research Rifampicin technical assistance
TB Infection Control

MDR-TB and XDR-TB: diagnostic approaches and considerations

Anna Tavares - June 17, 2014
The DR-TB Training Network, an online resource funded by USAID through the TB CARE II project, is pleased to announce that it will be hosting a webinar for our Francophone colleagues, to be presented ...
Keywords:
DR-TB DR-TB Training Network drug-resistant tuberculosis GeneXpert MTB/RIF MDR-TB Mycobacterium tuberculosis
MDR-TB Treatment & Prevention

Webinar in French - MDR-TB and XDR-TB: diagnostic approaches and considerations

Anna Tavares - June 17, 2014
The DR-TB Training Network, an online resource funded by USAID through the TB CARE II project, is pleased to announce that it will be hosting a webinar for our Francophone colleagues, to be presented ...
Keywords:
DR-TB DR-TB Training Network GeneXpert MTB/RIF MDR-TB Mycobacterium tuberculosis TB CARE II
MDR-TB Treatment & Prevention

GeneXpert as trusted testing tool

Hi, am Maopa from Fiji, There are 3 DOTs centres in Fiji and all have been provided with GeneXpert. There has not been any MDR TB reported for Fiji. Recently, we ran a geneXpert for a 3+ AFB case wit...
Keywords:
GeneXpert MTB/RIF Laboratory technical assistance
MDR-TB Treatment & Prevention

The Growing Problem of Multidrug-Resistant Tuberculosis in North Korea - PLoS

Sophie Beauvais - Aug. 2, 2013
Summary Points > In the absence of surveillance data, international aid to the North Korean national tuberculosis (TB) program has largely ignored the possibility that drug-resistant TB strains are...
Keywords:
Advocacy & Education GeneXpert MTB/RIF Publications & Research
MDR-TB Treatment & Prevention

Expert Panel Dec. 10-14: Scaling-up GeneXpert MTB/RIF

Sophie Beauvais - Dec. 8, 2012
Dear colleagues, Starting Monday, December 10, and running until Friday, December 14, we are pleased to host a virtual panel discussion on scaling-up the use of the GeneXpert MTB/RIF. In August,...
Keywords:
GeneXpert MTB/RIF Laboratory Program Management technical assistance Training
MDR-TB Treatment & Prevention

Challenges in Rolling-out the GeneXpert MTB/RIF Diagnostic Test in Resource-Limited Settings - May 9-20

Sophie Beauvais - May 9, 2011
Dear colleagues, Starting today, May 9, and running until May 20, GHDonline is pleased to host an expert panel discussion on the challenges of rolling-out the Xpert MTB/RIF diagnostic test, especi...
Keywords:
Clinical Assistance diagnostics GeneXpert MTB/RIF Laboratory Program Management Supply Chain TB CARE II technical assistance