Search results

Global Health Diagnostics

A rapid culture system uninfluenced by an inoculum effect increases reliability and convenience for TB DST

Madhukar Pai - June 9, 2018
This proof of concept study shows that a Disc Agarose Channel (DAC) system that utilizes microfluidics and imaging technologies and is fully automated is capable of tracking single cell growth to prod...
Keywords:
drug-resistant tuberculosis Drug Susceptibility Testing DST
Global Health Diagnostics

Announcement "Diego Zallocco - 5th course on Molecular Diagnosis of Drug Resistant TB", 19-27 November 2018, WHO Collaborating Centre, Milan, Italy

Andrea Cabibbe - May 2, 2018
Dear All, We are excited to announce that registration for the Diego Zallocco – 5th Course on Molecular Diagnosis of Drug Resistant TB (19-27 November 2018) is now OPEN. This eight-days course fo...
Keywords:
anti-microbial resistance drug resistance surveillance drug-resistant tuberculosis Molecular diagnostics molecular epidemiology Next Generation Sequencing
Global Health Diagnostics

Widespread use of incorrect PCR ramp rate negatively impacts multidrug-resistant tuberculosis diagnosis (MTBDRplus)

Brigitta Derendinger - Feb. 26, 2018
Recently we have showed that many laboratories worldwide use the incorrect ramp rate (speed of temperature change between cycles) setting on the PCR machine when using the MTBDRplus assay. This possib...
Keywords:
diagnostics drug resistance drug-resistant tuberculosis MTBDRplus Ramp rate
Global Health Diagnostics

A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis

Madhukar Pai - Jan. 6, 2018
In this paper, raw genotype–phenotype correlation data were extracted as part of a comprehensive systematic review to develop a standardised analytical approach for interpreting resistance associated ...
Keywords:
anti-microbial resistance drug-resistant tuberculosis Drug Susceptibility Testing DST mutation phenotypic
Global Health Diagnostics

To Test or Not to Test? Ending the Age-Old Debate for Drug-Resistant Tuberculosis

Madhukar Pai - May 28, 2017
Please read this important, powerful and provocative piece by Jen Furin and Helen Cox in CID: https://academic.oup.com/cid/article-abstract/doi/10.1093/cid/cix491/3854942/To-Test-or-Not-to-Test-End...
Keywords:
drug-resistant tuberculosis Drug Susceptibility Testing DST
Global Health Diagnostics

Tuberculosis innovations mean little if they cannot save lives

Madhukar Pai - May 2, 2017
In this paper, published today in eLife (open access), Jennifer Furin and I summarize the uptake of new tools such as GeneXpert, bedaquiline and delamanid, and identify the main barriers to scale-up a...
Keywords:
drug-resistant tuberculosis new tools
MDR-TB Treatment & Prevention

MSF responds to new WHO TB treatment and diagnostic recommendations

Michelle French - May 12, 2016
MSF response to WHO TB treatment and diagnostic recommendations http://www.msfaccess.org/about-us/media-room/press-releases/msf-response-who-tb-treatment-and-diagnostic-recommendations May 12, ...
Keywords:
DR-TB drug-resistant tuberculosis Guidelines MDRTB MDR TB multidrug-resistant tuberculosis
TB Infection Control

MDR-TB and XDR-TB: diagnostic approaches and considerations

Anna Tavares - June 17, 2014
The DR-TB Training Network, an online resource funded by USAID through the TB CARE II project, is pleased to announce that it will be hosting a webinar for our Francophone colleagues, to be presented ...
Keywords:
DR-TB DR-TB Training Network drug-resistant tuberculosis GeneXpert MTB/RIF MDR-TB Mycobacterium tuberculosis
MDR-TB Treatment & Prevention

TB Infection Control Webinar Series

Evgenia Markvardt - June 17, 2014
Dear GHDonline members, The DR-TB Training Network (USAID funded through the TB CARE II project) is pleased to announce a series of webinars focusing on TB infection control presented by Dr. Edward...
Keywords:
DR-TB drug-resistant tuberculosis infection control MDR-TB tb tuberculosis UVGI
MDR-TB Treatment & Prevention

MDR-TB in Pakistan

Julia Irani - Dec. 11, 2009
Greetings, I wanted to share a few short youtube clips highlighting the MDR-TB situation in Pakistan and Indus Hospital’s work reported by Dawn News, a national news channel of Pakistan. Dawn N...
Keywords:
Advocacy drug-resistant tuberculosis General Resources tb tuberculosis
MDR-TB Treatment & Prevention

DR-TB in Mumbai, India

Amy Madore - Sept. 4, 2009
http://worldfocus.org/blog/2009/09/02/mumbai-confronts-drug-resistant-tuberculosis-strain/7092/ This short video examines drug-resistant TB in Mumbai, the largest city in India and one of the most ...
Keywords:
drug-resistant tuberculosis India Mumbai video