David Bangsberg, MD, MPH

Recent Contributions

Food insecurity as a barrier to sustained antiretroviral therapy adherence in Uganda

May 13, 2010
BACKGROUND: Food insecurity is emerging as an important barrier to antiretroviral (ARV) adherence in sub-Saharan Africa and elsewhere, but little is known about the mechanisms through which food insecurity leads to ARV non-adherence and treatment interruptions. METHODOLOGY: We conducted in-depth, open-ended interviews with 47 individuals (30 women, 17 men) living ...

Reply to Different ways to score adherence questions

Feb. 12, 2009
Dear Ziad, the classic ACTG measure paper is: Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG Adherence Instruments; by Chesney, M. A., Chambers, D. B., Ickovics, J. R., Gifford, A. L., Neidig, J., Zwickl, B., Wu, A. W.; AIDS Care; Jun2000, Vol. 12 Issue 3, ...

Optimal Recall Period and Response Task for Self-Reported HIV Medication Adherence

Feb. 12, 2009
Self-reported measures of antiretroviral adherence vary greatly in recall time periods and response tasks. To determine which time frame is most accurate, we compared 3-, 7-day, and 1-month self-reports with data from medication event monitoring system (MEMS). To determine which response task is most accurate we compared three different 1-month ...

Diagnostic value of different adherence measures using electronic monitoring and virologic failure as reference standards

Jan. 27, 2009
This study evaluates different measures of adherence within a single-center HIV cohort. The study compares 3 measures of self-reported non-adherence: (1) VSA, (2) SHCS-AQ and (3) the European HIV Treatment Questionnaire (EHTQ) – using electronic medication monitors as a referent group. The authors report four key findings from the study: ...

Not All Missed Doses Are the Same: Sustained NNRTI Treatment Interruptions Predict HIV Rebound at Low-to-Moderate Adherence Levels

Dec. 5, 2008
Monitoring for virologic failure is challenging in resource-limited settings, particularly because of cost constraints. Adherence is an important predictor of virologic rebound and drug resistance. Many studies in sub-Saharan Africa have found that average % adherence among patients in resource-limited settings is exceptional. However, average % adherence does not capture ...

Recent Recommendations

None at this time.