Nick joined the University of Oxford in 1991 as the director of the Wellcome Trust Clinical Research Unit (now OUCRU) in Vietnam, where for 5 years he conducted clinical studies on malaria, tetanus, diphtheria, dengue and typhoid. On return to the UK he studied staphylococcal disease as a Wellcome Trust Career Development Fellow (1997 to 2002), and was Deputy Director of the Centre for Tropical Medicine at Oxford from 1999 to 2003. Since 2003 he has been Director of the Wellcome Trust Thailand/Laos Major Overseas Programme (MOP), a 36 year old collaboration between the University of Oxford and the Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. In 2006 he was awarded the Chalmers Medal by the Royal Society for Tropical Medicine and Hygiene for contributions to tropical medicine research.
The Mahidol-Oxford Tropical Medicine Research Unit (MORU), which hosts the WT Thailand/Laos MOP, is a large and productive tropical research unit, employing over 700 staff, with a diverse research portfolio. MORU conducts clinical research on malaria, melioidosis, leptospirosis, rickettsial infections, influenza, dengue, tuberculosis and other communicable diseases afflicting populations in the tropics throughout Asia and beyond.
Although he is involved in setting the strategic direction of all of the Programme’s research, his personal major research interests are in the diagnosis, pathophysiology, treatment and prevention of malaria, rickettsial infections, leptospirosis, staphylococcal disease and melioidosis.